The anti‐cancer drug cisplatin induces HSP25 in Ehrlich ascites tumor cells by a mechanism different from transcriptional stimulation influencing predominantly HSP25 translation
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منابع مشابه
The utilization of unesterified palmitate by Ehrlich ascites tumor cells.
Ehrlich ascites tumor cells have been shown to take up long chain free fatty acids from albumin-FFA’ complexes very rapidly in vitro. The uptake during the 1st min of exposure of the cells is dependent on the FFA-albumin molar ratio in the medium (I? 2). Most of the FFA initially taken up is present in unesterified form, and at least 50% of it is reversibly bound (2). The initial FFA uptake is ...
متن کاملOn Perfused Ehrlich Ascites Tumor Cells
In an attempt to overcome resistance of hypoxic cells to radiotherapy, the combination of a hematoporphyrin derivative (Hpd) and 2-deoxy-D-glu'cose (2-DG), a promising radiomodifier, was evaluated by assessing the alterations in phosphorylated metabolites and bioenergetics induced in perfused Ehrlich :lscites tumor (EAT) cells, using Phosphorus31 Magnetic Resonance Spectroscopy (JiP-MRS). By re...
متن کاملGracilaria edulis extract induces apoptosis and inhibits tumor in Ehrlich Ascites tumor cells in vivo
BACKGROUND Marine environment is inestimable for their chemical and biological diversity and therefore is an extraordinary resource for the discovery of new anticancer drugs. Recent development in elucidation of the mechanism and therapeutic action of natural products helped to evaluate for their potential activity. METHODS We evaluated Gracilaria edulis J. Ag (Brown algae), for its antitumor...
متن کاملPurification of interferon from mouse Ehrlich ascites tumor cells.
Interferon production was induced in mouse Ehrlich ascites tumor cells by infection with Newcastle disease virus. The interferon produced was purified by precipitation with ammonium sulfate, chromatography on carboxymethyl-Sephadex, treatment with blue dextran and polyethylene glycol, gel filtration on Bio-Gel P-60 and Bio-Gel P-200, chromatography on phosphocellulose, isoelectric focusing, and...
متن کاملRelease of free fatty acids from Ehrlich ascites tumor cells.
Ehrlich ascites tumor cells release free fatty acids (FFA) during in vitro incubation in media that contain albumin. The released FFA are derived by lipolysis from endogenous lipid esters. Addition of glucose to the incubation medium greatly decreases the quantity of fatty acid released by the cells. Cyanide, which inhibits endogenous lipid oxidation but not lipolysis, increases the quantity of...
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ژورنال
عنوان ژورنال: International Journal of Cancer
سال: 1996
ISSN: 0020-7136,1097-0215
DOI: 10.1002/(sici)1097-0215(19960611)66:6<790::aid-ijc14>3.3.co;2-z